P-REX1-Independent, Calcium-Dependent RAC1 Hyperactivation in Prostate Cancer
نویسندگان
چکیده
منابع مشابه
A Rac1-Independent Role for P-Rex1 in Melanoblasts
TO THE EDITOR Given the recent discovery of RAC1activating mutations in melanoma, and our finding that PIP3-dependent Racexchanger 1 (PREX1) is overexpressed and drives metastasis in this cancer, an important question is to establish whether the functions of P-Rex1 are mediated specifically by Rac alone (Lindsay et al., 2011; Berger et al., 2012). Here we describe a Rac1-independent in vivo rol...
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ژورنال
عنوان ژورنال: Cancers
سال: 2020
ISSN: 2072-6694
DOI: 10.3390/cancers12020480